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national antimicrobial resistance monitoring system

Antimicrobial Resistance and Whole Genome Sequencing – What is Changing?

To better understand antibiotic resistance (AMR) in bacteria, agencies within USDA, the Food and Drug Administration (FDA), the Centers for Disease Control and Prevention (CDC), and other federal and state partners work collaboratively through the National Antimicrobial Resistance Monitoring System (NARMS). Recent ground-breaking scientific advances are helping NARMS partners to improve their understanding about how some disease-causing bacteria can become resistant to antibiotics.

USDA’s Role in Combatting Antimicrobial Resistance

Scientists from USDA developed the tools to mass produce penicillin, which was used for treating wounded soldiers over 70 years ago during World War II. Antibiotics are still important in treating microbial infection in humans, animals, and plants. However, microbes can develop resistance to some antibiotics, making them less effective. USDA agencies continue to work on numerous issues related to antibiotics and antimicrobial resistance (AMR).

Proactive Efforts by U.S. Federal Agencies Enable Early Detection of New Antibiotic Resistance

Just over a year ago, President Obama released a National Action Plan for Combating Antibiotic Resistant Bacteria. As part of that plan, he also charged the Department of Defense (DoD), Department of Agriculture (USDA) and Department of Health and Human Services (HHS) with co-chairing a Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (Advisory Council). In the past year, our three agencies and the Council have held numerous stakeholder meetings, made new discoveries, and undertaken new research to preserve the effectiveness of antibiotics.

In recent weeks, our three agencies have made some important discoveries regarding antibiotic resistance in the United States. Earlier this week, the Department of Defense notified stakeholders that its Multidrug-resistant Organism Repository and Surveillance Network (MRSN) at the Walter Reed Institute of Research had identified the first colistin-resistant mcr-1 E. coli in a person in the United States. A USDA and HHS search for colistin-resistant bacteria in food animals, retail meats and people also has found colistin-resistant E. coli in a single sample from a pig intestine.